| Keith Urban | Country musicIndependent musicPop | 12 |
| Carrie Underwood | Country musicRockPop RockPop | 19 |
| U2 | RockAlternative rock | 6 |
| Leonid Utyosov | Soviet songPop genreJazzTangoSoundtrack | 27 |
| Uncle Trainz | Rap | 1 |
| Dominique Young Unique | Dance music | 1 |
| Uriah Heep | RockBallad | 30 |
| Lyubov Uspenskaya | ChansonPop genrePop | 45 |
| Lil Uzi Vert | RapPop | 10 |
| Unheilig | RockPop RockPop | 4 |
| Brendon Urie | Pop | 1 |
| Sub Urban | Electronic musicAlternative rock | 5 |
